2015: Bert Vogelstein, M.D.
2014: Jennifer Doudna, Ph.D., and Emmanuelle Charpentier, Ph.D.
2013: David Julius, Ph.D.
2012: Victor Ambros, Ph.D. and Gary Ruvkun, Ph.D.
2011: Napoleone Ferrara, M.D.
2010: Erik De Clercq, M.D., Ph.D. and Anthony S. Fauci, M.D.
2009: Axel Ullrich, Ph.D.
2008: Marc Feldmann and Sir Ravinder Maini
2006: Craig C. Mello, Ph.D.
Bert Vogelstein, M.D.
Clayton Professor of Oncology and Pathology, Johns Hopkins University, Director, Ludwig Center for Cancer Genetics & Therapeutics, Johns Hopkins Kimmel Cancer Center Investigator, Howard Hughes Medical Institute
For his breakthroughs in oncology research, which have spanned more than two decades and have formed the basis of modern cancer research.
Jennifer Doudna, Ph.D.
Howard Hughes Medical Institute Investigator and Li Ka Shing Chancellor's Chair in Biomedical and Health Sciences, Professor of Biochemistry, Biophysics and Structural Biology, University of California, Berkeley
Emmanuelle Charpentier, Ph.D.
Hannover Medical School and Helmholtz Centre for Infection Research (HZI), Germany and The Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Sweden
For their co-discovery of a new method for precisely manipulating genetic information in ways that should produce new insights in health and disease, and may lead to the discovery of new targets for drug development.
David Julius, Ph.D.
Professor and Chair, Department of Physiology, University of California San Francisco
For his discovery of the molecular mechanism that controls thermosensation (sensory perception of temperature) and elucidation of the role this mechanism plays in the sensation of acute and inflammatory pain.
Victor Ambros, Ph.D.
Professor of Molecular Medicine, University of Massachusetts Medical School
Gary Ruvkun, Ph.D.
Harvard Medical School Professor of Genetics at Massachusetts General Hospital
For their co-discovery of microRNAs (miRNAs) as central regulators of gene expression and development.
Napoleone Ferrara, M.D.
Genentech Fellow, San Francisco, California, USA
For his research on angiogenesis, the process of new blood vessel formation that plays a key role in cancer proliferation and a number of other diseases.
Erik De Clercq, M.D., Ph.D.
Professor Emeritus, Rega Institute for Medical Research, Leuven, Belgium
Anthony S. Fauci, M.D.
Director, National Institute of Allergy and Infectious Diseases, the National Institutes of Health, Bethesda, MD
For their pioneering work in understanding and combating viral diseases, particularly HIV/AIDS
Axel Ullrich, Ph.D.
Director of the Department of Molecular Biology, Max Planck Institute of Biochemistry, Germany
For his pioneering work in applying molecular biology and molecular cloning to the discovery of protein therapeutics for the treatment of a wide range of diseases, including diabetes and cancer.
Professor Marc Feldmann FMedSci, FAA, FRS and Emeritus Professor Sir Ravinder Maini, FMedSci, FRCP, FRS
Kennedy Institute of Rheumatology, Imperial College, London, U. K
For their role in the discovery of tumor necrosis factor-alpha as an effective therapeutic target for rheumatoid arthritis and other chronic inflammatory conditions.
Craig C. Mello, Ph. D.
Professor of Molecular Medicine at the University of Massachusetts Medical
School, Worchester, Massachusetts, U. S. A.
For his role in the discovery of RNA interference and the elucidation of its biological functions.