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1956
J.F. Heymans Prize, State University of Ghent (Belgium).
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1965
Carl Wilhelm Scheele Prize, Pharmaceutical Society of Sweden, Stockholm.
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1970
Taylor Manor Hospital Psychiatric Award, Baltimore, Maryland (USA).
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1978
Adriaan Stevens Prize, Flemish Chemical Society, Ghent (Belgium).
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1978
Johnson Medal for Extraordinary Achievements, New Brunswick, New Jersey (USA).
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1982
Gairdner Foundation Award, Toronto (Canada).
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1984
Award in Medicinal Chemistry, American Chemical Society (USA).
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1984
Galenus Prize (Journal du Médecin, Journal du Pharmacien (Belgium) for ketoconazole (1984), and astemizole (1985).
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1984
Quinquennial Prize for Pharmaceutical and Therapeutic Sciences, Belgian Royal Academy of Medicine.
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1986
Chauncey D. Leake Award, University of California, San Francisco (USA).
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1987
Discoverers' Award, Pharmaceutical Manufacturers Association, Washington DC (USA).
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1989
Dirk van Os Medal, Groningen University Fund Foundation (the Netherlands).
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1990
Jacob Henle Medal, Georg-August University, Göttingen (Germany).
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1990
Carothers Award, American Chemical Society, Delaware Section (USA).
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1990
Golden Jaroslav Heyrovsky Medal, Czechoslovakian Academy of Science, Brezna (Czechoslovakia).
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1990
Distinguished Service Award, American College of Clinical Pharmacology, Nevada (USA).
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1991
Decoration of the Order of the Rising Sun, Golden Rays with Neck Ribbon, conferred by His Majesty the Emperor of Japan.
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1991
Grand Officer of the Order of the Crown, Belgian Royal Academy of Medicine.
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1993/
1996
Honorary Professor (1993) and Consulting Professor (1994/1996) in Dermatology, Stanford University (USA).
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1995
Galenus Prize for Risperdal® (risperidone), Canada.
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1996
Galenus Prize for Risperdal® (risperidone), France.
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1996
The Pharmaceutical Discoverer's Award, NARSAD (National Alliance for Research on Schizophrenia and Depression) (USA).
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1996
Grand Officer of the Order of Leopold, Belgian Royal Academy of Medicine.
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1996
International Galenus Prize for Risperdal® (risperidone), London (UK).
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1997
Visiting Professor, Faculty of Medicine, University of Nanjing, China.
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1998
"Chaire Pierre Dumont" Award 1998-1999, School of Pharmacy, Catholic University of Louvain, Brussels, Belgium.
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1999
Friendship Award, Belgian American Chamber of Commerce.
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1999
Gold Medal, Royal Flemish Academy of Belgium for the Sciences and Arts.
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1999
Flemish Entrepreneur of the Century, De Standaard newspaper, Belgium.
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2000
Medal of the Institute of Pharmaceutical Chemistry, University of Lille 2 , France.
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2000
CINP-Pfizer Pioneers in Psychopharmacology Award.
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2002
Homeland honorary member of the Royal Belgian Academy of Medicine.
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2002
Honorary Dean of Xi Jing University, Xian (China).